Author

P. Fitzgerald-Bocarsly

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell signaling & trafficking· 3 Research Focus:cell type annotation· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:differential expression· 2 Assay:flow cytometry· 2 Organism:mouse· 2

Frequent Co-Authors

J. Dai· 2 shared S. Singh· 2 shared A. Beaulieu· 1 shared A. Davidow· 1 shared A. L. Codrington· 1 shared A. Lemenze· 1 shared A. Rivera· 1 shared A. Wang· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

J. Dai

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Metabolic Deficiencies Underlie Plasmacytoid Dendritic Cell Exhaustion After Viral Infection

T. T. Greene, Y. Jo, M. Macal, Z. Fang, F. S. Khatri, A. L. Codrington, K. R. Kazane, C. Chiale, E. Akbulut, S. Swaminathan, Y. Fujita, P. Fitzgerald-Bocarsly, T. Cordes, C. Metallo, D. A. Scott, E. I. Zuniga

This study identifies LDHB as a key regulator of pDC IFN-I production and metabolic capacity during viral infection, linking metabolic deficiencies to pDC exhaustion and its dual role in immunity and pathology.

bioRxiv · Feb 28, 2024 · PreprintImmunology

Interferon epsilon restricts Zika virus infection in the female reproductive tract

C. Xu, A. Wang, L. Ebraham, L. Sullivan, C. Tasker, V. Pizutelli, J. Couret, C. Hernandez, P. Q. Deb, L. Fritzky, S. Subbian, N. Gao, Y. Lo, M. Salvatore, A. Rivera, , T. L. Chang

This study shows that IFNε protects against vaginal ZIKV infection in mice by maintaining epithelial integrity and is effective even without IFNAR1 signaling.

PNAS Nexus · Oct 25, 2023Peer-reviewedImmunology

TLR4 signaling in presence of HIV-induced activation enhances programmed death ligand-1 expression on human plasmacytoid dendritic cells and modulates their function

M. Patel, S. Singh, A. Davidow, J. Dai, P. Fitzgerald-Bocarsly

This study shows that TLR4 signaling in HIV-infected individuals enhances PD-L1 expression and modulates pDC function, contributing to immune suppression.

bioRxiv · Jul 5, 2022 · PreprintImmunology

Conclusive Identification of Senescent T Cells Reveals Their Abundance in Aging Humans

R. I. Martinez Zamudio, H. K. Dewald, T. Vasilopoulos, L. Gittens-Williams, P. Fitzgerald-Bocarsly, U. Herbig

The paper identifies senescent T cells in aging humans and shows their abundance increases with age, contributing to immune decline.

bioRxiv · Jun 17, 2020Cell Biology

HDAC inhibitors decrease TLR7/9-mediated human plasmacytoid dendritic cell activation by interfering with IRF-7 and NF-қB signaling

D. B. Descalzi-Montoya, J. Dai, S. Singh, P. Fitzgerald-Bocarsly

bioRxiv · May 9, 2020 · PreprintImmunology