Author

P. G. Frank

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

C. Ben Hassen· 2 shared J. L. Gutierrez-Pajares· 2 shared A. Girault· 1 shared A. J. Garcia-Saez· 1 shared A. Le Pape· 1 shared A. Lefevre· 1 shared A. Robert· 1 shared C. Goupille· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBiochemistry

C. Ben Hassen

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Author profile →

3 papers

Recent·Most cited

Curcumin and NCLX Inhibitors Share Anti-Tumoral Mechanisms in Microsatellite-Instability-Driven Colorectal Cancer

M. Gueguinou, S. Ibrahim, J. Bourgeais, A. Robert, T. Pathak, X. Zhang, D. Crottes, J. Dupuy, D. Ternant, V. Monbet, R. Guibon, H. Flores-Romero, A. Lefevre, S. Lerondel, A. Le Pape, , T. Lecomte

This study identifies NCLX as a therapeutic target in MSI-driven CRC, showing that curcumin and NCLX inhibitors induce anti-tumoral effects through mitochondrial calcium overload and apoptosis.

bioRxiv · Jan 18, 2022Cancer Biology

Development of a novel HPTLC-based method for the simultaneous quantification of clinically relevant lipids from cells and tissue extracts

M. Pinault, C. Guimaraes, C. Ben Hassen, J. L. Gutierrez-Pajares, S. Chevalier, C. Goupille, P. Bernard-Savary, P. G. Frank

The paper develops and validates an HPTLC method to simultaneously quantify free cholesterol, cholesteryl esters, non-esterified fatty acids, and triglycerides from cells and tissue extracts.

bioRxiv · Sep 23, 2019 · PreprintBiochemistry

Oxidized products of α-linolenic acid negatively regulate cellular survival and motility of breast cancer cells

J. L. Gutierrez-Pajares, C. Ben Hassen, C. Oger, J.-M. Galano, T. Durand, P. G. Frank

This study evaluates plant-derived oxidized α-linolenic acid products for their cytotoxic and anti-migratory effects on breast cancer cells, finding three PhytoPs enhance doxorubicin's efficacy and inhibit migration.

bioRxiv · May 24, 2019Cancer Biology