Author

S. Lerondel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. Le Pape· 2 shared A. Bokhobza· 1 shared A. CHAUCHEREAU· 1 shared A. Fiorio Pla· 1 shared A. Folcher· 1 shared A. Girault· 1 shared A. Haustrate· 1 shared A. J. Garcia-Saez· 1 shared

Activity by Year

2016-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCancer Biology

A. Le Pape

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Curcumin and NCLX Inhibitors Share Anti-Tumoral Mechanisms in Microsatellite-Instability-Driven Colorectal Cancer

M. Gueguinou, S. Ibrahim, J. Bourgeais, A. Robert, T. Pathak, X. Zhang, D. Crottes, J. Dupuy, D. Ternant, V. Monbet, R. Guibon, H. Flores-Romero, A. Lefevre, S. Lerondel, A. Le Pape, , T. Lecomte

This study identifies NCLX as a therapeutic target in MSI-driven CRC, showing that curcumin and NCLX inhibitors induce anti-tumoral effects through mitochondrial calcium overload and apoptosis.

bioRxiv · Jan 18, 2022Cancer Biology

Expression of neuronal Na+ leak channel, NALCN, provides for persistent invasion of metastasizing cancer cells

O. Iamshanova, D. Gordienko, A. Folcher, A. Bokhobza, G. Shapovalov, D. Kannancheri-Puthooru, P. Mariot, L. Allart, E. Desruelles, C. Spriet, R. Diez, T. Oullier, S. Marionneau-Lambot, L. Brisson, S. Geraci, , N. Prevarskaya

The paper identifies NALCN as a key player in metastatic cancer cell invasion by generating Ca2+ oscillations that drive Src kinase activity and proteolytic enzyme secretion.

bioRxiv · Aug 13, 2020 · PreprintCell Biology

Regulation of eIF4F complex by the peptidyl prolyl isomerase FKBP7 in taxane-resistant prostate cancer

M. F. GARRIDO, N. J. MARTIN, C. GAUDIN, F. Commo, N. AL NAKOUZI, L. FAZLI, E. DEL NERY, J. Camonis, F. Perez, S. LERONDEL, A. LE PAPE, H. ABOU-HAMDAN, M. Gleave, Y. Loriot, L. DESAUBRY, , A. CHAUCHEREAU

This study identifies FKBP7 as a molecular chaperone that regulates the eIF4F complex in taxane-resistant prostate cancer, and shows that inhibiting eIF4A can overcome resistance.

bioRxiv · Dec 22, 2016Cancer Biology