Author

P. Gangatirkar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1

Frequent Co-Authors

C. Hall· 3 shared A. Hempel· 2 shared A. L. Samson· 2 shared H. Anderton· 2 shared J. Day· 2 shared J. Hildebrand· 2 shared J. M. Murphy· 2 shared J. Rickard· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCell Biology

C. Hall

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Author profile →

3 papers

Recent·Most cited

An immunohistochemical atlas of necroptotic pathway expression

S. Chiou, A. Al-Ani, Y. Pan, K. Patel, I. Kong, L. Whitehead, A. Light, S. Young, M. Barrios, C. Sargeant, P. Rajasekhar, L. Zhu, A. Hempel, A. Lin, J. Rickard, , A. L. Samson

The paper develops automated immunohistochemistry protocols to detect necroptotic pathway proteins in mouse and human tissues, revealing heterogeneity and disease-related changes in expression.

bioRxiv · Oct 31, 2023Cell Biology

MLKL deficiency protects against low-grade, sterile inflammation in aged mice

E. C. Tovey, S. E. Garnish, J. Day, H. Anderton, S. Chiou, A. Hempel, C. Hall, K. Patel, P. Gangatirkar, C. S. N. Li Wai Suen, A. Garnham, A. J. Kueh, U. Nachbur, A. L. Samson, J. M. Murphy, J. M. Hildebrand

This study shows that MLKL deficiency reduces age-related sterile inflammation in mice by preserving lymphocyte levels and reducing inflammatory infiltrates in tissues.

bioRxiv · Oct 17, 2022 · PreprintImmunology

Missense mutations in the MLKL brace region lead to lethal neonatal inflammation in mice and are present in high frequency in humans.

J. Hildebrand, M. Kauppi, I. Majewski, Z. Liu, A. Cox, S. Miyake, C. Hall, E. Petrie, M. Silk, M. Tanzer, S. Young, S. Garnish, J. Corbin, M. Stutz, P. Gangatirkar, , Venhoff

This study identifies a missense mutation in MLKL causing lethal neonatal inflammation in mice and links it to increased frequency in human autoinflammatory disease.

bioRxiv · May 15, 2019 · PreprintCell Biology