Inhibition of PLK1-dependent EBNA2 phosphorylation promotes lymphomagenesis in EBV-infected mice.
X. Zhang, P. Schuhmachers, A. Mourao, P. Giansanti, A. Murer, S. Thumann, C. Kuklik-Roos, S. Beer, S. M. Hauck, W. Hammerschmidt, R. Küppers, B. Küster, M. Raab, K. Strebhardt, M. Sattler, , B. Kempkes
The paper shows that inhibiting PLK1-dependent EBNA2 phosphorylation enhances EBNA2 activity, promoting lymphoma development in EBV-infected mice.
bioRxiv · Mar 29, 2021 · PreprintCancer Biology