Author

A. Mourao

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

M. Sattler· 3 shared A. Czarna· 2 shared A. Matsuda· 2 shared G. Dubin· 2 shared K. Pyrc· 2 shared M. Pachota· 2 shared Y. Chykunova· 2 shared A. Dabrowska· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersMicrobiology

M. Sattler

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Biochemically validated structural model of the 15-subunit IFT-B complex

N. A. Petriman, M. Loureiro-Lopez, M. Taschner, N. K. Zacharia, M. M. Georgieva, N. Boegholm, A. Mourao, R. B. Russell, J. S. Andersen, E. Lorentzen

The paper presents a biochemically validated structural model of the 15-subunit IFT-B complex using AlphaFold and experimental validation techniques.

bioRxiv · Aug 20, 2022 · PreprintBiochemistry

Despite the odds: formation of the SARS-CoV-2 methylation complex.

A. Matsuda, J. Plewka, Y. Chykunova, A. N. Jones, M. Pachota, M. Rawski, A. Mourao, A. Karim, L. Kresik, K. Lis, I. Minia, K. Hartman, R. Sonani, G. Dubin, M. Sattler, , A. Czarna

This study demonstrates that SARS-CoV-2 proteins nsp14, nsp10, and nsp16 form a heterotrimer complex, which modulates nsp14's exonuclease activity and protects viral RNA.

bioRxiv · Jan 25, 2022Microbiology

Inhibition of PLK1-dependent EBNA2 phosphorylation promotes lymphomagenesis in EBV-infected mice.

X. Zhang, P. Schuhmachers, A. Mourao, P. Giansanti, A. Murer, S. Thumann, C. Kuklik-Roos, S. Beer, S. M. Hauck, W. Hammerschmidt, R. Küppers, B. Küster, M. Raab, K. Strebhardt, M. Sattler, , B. Kempkes

The paper shows that inhibiting PLK1-dependent EBNA2 phosphorylation enhances EBNA2 activity, promoting lymphoma development in EBV-infected mice.

bioRxiv · Mar 29, 2021 · PreprintCancer Biology

Acriflavine, a clinically aproved drug, inhibits SARS-CoV-2 and other betacoronaviruses

V. Napolitano, A. Dabrowska, K. Schorpp, A. Mourao, E. Barreto-Duran, M. Benedyk, P. Botwina, S. Brandner, M. Bostock, Y. Chykunova, A. Czarna, G. Dubin, T. Frohlich, M. Hoelscher, M. Jedrysik, , K. Pyrc

This study identifies acriflavine as a potent inhibitor of SARS-CoV-2 and other betacoronaviruses, effective in cellular models, in vivo, and ex vivo.

bioRxiv · Mar 20, 2021Microbiology