Author

R. Küppers

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:database / resource· 1

Frequent Co-Authors

M. A. Weniger· 2 shared A. Akalin· 1 shared A. Mourao· 1 shared A. Murer· 1 shared A. Pfaus· 1 shared A. Reisser· 1 shared A. Rosenwald· 1 shared A. Vilas-Zornoza· 1 shared

Activity by Year

2021-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersCancer Biology

M. A. Weniger

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A new type of transcriptional reprogramming by an IRF4 mutation in lymphoma

N. Schleussner, P. Cauchy, V. Franke, M. Giefing, O. Fornes, N. Vankadari, S. Assi, M. Costanza, M. A. Weniger, A. Akalin, I. Anagnostopoulos, T. Bukur, M. G. Casarotto, F. Damm, O. Daumke, , R. Grosschedl

This study identifies a mutation in IRF4 that alters DNA-binding specificity and gene regulation in lymphoma, leading to disease-specific gene up-regulation.

bioRxiv · Dec 29, 2022 · PreprintCancer Biology

An Atlas of Cells in the Human Tonsil

R. Massoni-Badosa, P. Soler-Vila, S. Aguilar-Fernandez, J. C. Nieto, M. Elosua-Bayes, D. Marchese, M. Kulis, A. Vilas-Zornoza, M. M. Bühler, S. Rashmi, C. Alsinet, G. Caratu, C. Moutinho, S. Ruiz, P. Lorden, , H. Heyn

The paper creates a comprehensive cell atlas of the human tonsil using single-cell multi-omics data, identifying 121 cell types and uncovering regulatory mechanisms and disease-related changes.

bioRxiv · Jun 24, 2022Immunology

Inhibition of PLK1-dependent EBNA2 phosphorylation promotes lymphomagenesis in EBV-infected mice.

X. Zhang, P. Schuhmachers, A. Mourao, P. Giansanti, A. Murer, S. Thumann, C. Kuklik-Roos, S. Beer, S. M. Hauck, W. Hammerschmidt, R. Küppers, B. Küster, M. Raab, K. Strebhardt, M. Sattler, , B. Kempkes

The paper shows that inhibiting PLK1-dependent EBNA2 phosphorylation enhances EBNA2 activity, promoting lymphoma development in EBV-infected mice.

bioRxiv · Mar 29, 2021 · PreprintCancer Biology