Author

P. Gissen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 4 Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cell-cell communication· 1 Assay:electronic health records· 1 Assay:imaging· 1

Frequent Co-Authors

A. Agrotis· 1 shared A. Cavedon· 1 shared A. Chakrapani· 1 shared A. Frassetto· 1 shared A. Gregory· 1 shared A. Morris· 1 shared A. Munteanu· 1 shared A. Papandreou· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

A. Agrotis

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Novel 3D Approach to Model Non-Alcoholic Fatty Liver Disease using human Pluripotent Stem Cells

C. M. Morell, S. G. Tilson, R. A. Tomaz, A. Shahsavari, A. Munteanu, G. Canu, B. T. Wesley, M. Perrin, I. Geti, S. Mukhopadhyay, F. Mazzacuva, P. Gissen, J. Garcia-Bernardo, M. Bachman, C. A. Rimland, , L. Vallier

This paper develops a 3D multicellular model of NAFLD using hiPSC-derived liver cells to study disease mechanisms and interactions.

bioRxiv · Feb 7, 2024 · PreprintCell Biology

The incidence of movement disorders increases with age and contrasts with subtle and limited neuroimaging abnormalities in argininosuccinic aciduria.

S. Gurung, S. Karamched, D. P. Perocheau, K. Seunarine, T. Balwin, L. Touramanidou, C. Duff, N. Elkhateeb, K. Stepien, R. Sharma, A. Morris, T. Hartley, L. Crowther, S. Grunewald, M. Cleary, , J. Baruteau

This study investigates movement disorders in argininosuccinic aciduria (ASA), finding they increase with age and show specific neuroimaging abnormalities not seen in mouse models.

bioRxiv · Oct 10, 2023 · PreprintGenetics

Cardiac glycosides restore autophagy flux in an iPSC-derived neuronal model of WDR45 deficiency

A. Papandreou, N. Singh, L. Gianfrancesco, D. Budinger, K. Barwick, A. Agrotis, C. Luft, Y. Shao, A.-S. Lenaerts, A. Gregory, S. Y. Jeong, P. Hogarth, S. Hayflick, S. Barral, J. Kriston-Vizi, , R. Ketteler

This study identifies cardiac glycosides that restore autophagy and gene expression in an iPSC model of WDR45 deficiency, suggesting potential therapeutic applications for BPAN.

bioRxiv · Sep 13, 2023 · PreprintCell Biology

ER-PM contacts regulate apical domain formation in hepatocytes

G. H. Chung, J. J. Burden, M. Lorvellec, P. Gissen, C. J. Stefan

This study investigates how ER-PM contacts influence apical domain formation in hepatocytes by regulating lipid distribution and polarity.

bioRxiv · Apr 23, 2020 · PreprintCell Biology