P. H. Zwart

This paper evaluates a data processing pipeline for solving protein structures from radiation-damaged tomograms of nanocrystals using simulations.

This paper develops a numerical quadrature method to efficiently evaluate intensity-based likelihood functions in crystallography, improving the use of marginal diffraction data for structure determination.

This study develops an optical method to control PTP1B activity and shows that small activity changes lead to large shifts in phosphorylation of its targets.