Author

J. M. Fox

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Bioengineering· 1 Cell Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. O. Hassan· 2 shared E. S. Winkler· 2 shared J. B. Case· 2 shared L. E. Gralinski· 2 shared M. S. Diamond· 2 shared N. M. Kafai· 2 shared R. E. Chen· 2 shared R. S. Baric· 2 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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2 shared papersMicrobiology

A. O. Hassan

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

A biophysical rationale for the selective inhibition of PTP1B over TCPTP by nonpolar terpenoids

A. J. Friedman, H. M. Padgette, L. Kramer, E. T. Liechty, G. W. Donovan, J. M. Fox, M. R. Shirts

The paper investigates how nonpolar terpenoids selectively inhibit PTP1B over TCPTP by disrupting conserved allosteric networks, with differences in amino acid conservation at specific sites enabling this selectivity.

bioRxiv · Apr 17, 2023 · PreprintBioengineering

Identification of CD317-Positive Pro-inflammatory Immune Stromal Cells in Human Mesenchymal Stromal Cell Preparations

A. G. Kay, J. M. Fox, J. Hewitson, A. Stone, S. Robertson, S. R. James, X.-N. Wang, E. Kapasa, X. B. Yang, P. G. Genever

The paper identifies CD317-positive pro-inflammatory immune stromal cells in human MSC preparations and shows their distinct functional roles in inflammation and immunomodulation.

bioRxiv · Feb 10, 2022 · PreprintCell Biology

A single intranasal dose of chimpanzee adenovirus-vectored vaccine confers sterilizing immunity against SARS-CoV-2 infection

A. O. Hassan, N. M. Kafai, I. P. Dmitriev, J. M. Fox, B. Smith, I. B. Harvey, R. E. Chen, E. S. Winkler, A. W. Wessel, J. B. Case, E. Kashentseva, B. T. McCune, A. L. Bailey, H. Zhao, L. A. VanBlargan, , M. S. Diamond

A single intranasal dose of ChAd-SARS-CoV-2-S vaccine prevents SARS-CoV-2 infection and likely confers sterilizing immunity in mice.

bioRxiv · Jul 16, 2020 · PreprintMicrobiology

Potently neutralizing human antibodies that block SARS-CoV-2 receptor binding and protect animals

S. J. Zost, P. Gilchuk, J. B. Case, E. Binshtein, R. E. Chen, J. X. Reidy, A. Trivette, R. S. Nargi, R. E. Sutton, N. Suryadevara, L. E. Williamson, E. C. Chen, T. Jones, S. Day, L. Myers, , J. E. Crowe

The paper identifies potent neutralizing antibodies against SARS-CoV-2 that block receptor binding and protect animals, providing insights for vaccine and therapy development.

bioRxiv · May 22, 2020Immunology

Minimally disruptive optical control of protein tyrosine phosphatase 1B

A. Hongdusit, P. H. Zwart, B. Sankaran, J. M. Fox

This study develops an optical method to control PTP1B activity and shows that small activity changes lead to large shifts in phosphorylation of its targets.

bioRxiv · Jan 14, 2020Biochemistry