Author

P. Hematti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Bioengineering· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:flow cytometry· 1 Assay:imaging· 1 Organism:non-human primate· 1 Assay:proteomics· 1

Frequent Co-Authors

C. M. Capitini· 2 shared N. S. Callander· 2 shared A. Hudson· 1 shared A. Kumar· 1 shared A. M. Cunningham· 1 shared A. Pagenkopf· 1 shared A. Papadas· 1 shared A. Prabahar· 1 shared

Activity by Year

2018-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

C. M. Capitini

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Author profile →

5 papers

Recent·Most cited

Investigating the in vivo biodistribution of extracellular vesicles isolated from various human cell sources using positron emission tomography

Z. T. Rosenkrans, A. S. Thickens, J. A. Kink, E. Aluicio-Sarduy, J. W. Engle, P. Hematti, R. Hernandez

This study uses PET imaging to track the in vivo biodistribution of extracellular vesicles from different human cell sources, revealing tissue-specific uptake patterns and highlighting the importance of cell source selection for therapeutic applications.

Molecular Pharmaceutics · Aug 21, 2024Peer-reviewedBioengineering

Modulating Mesenchymal Stromal Cell Microenvironment Alters Exosome RNA Content and Ligament Healing Capacity

C. Chamberlain, A. Prabahar, J. Kink, E. Mueller, Y. Li, S. Yopp, C. Capitini, M. William, P. Hematti, R. Vanderby, P. Jiang

This study shows that altering the microenvironment of mesenchymal stromal cells changes exosome RNA content and improves ligament healing in rats.

Stem Cells · Jul 8, 2024Peer-reviewedCell Biology

Inflammatory CD4/CD8 double positive human T cells arise from reactive CD8 T cells and are sufficient to mediate GVHD pathology

N. J. Hess, D. P. Turicek, J. Riendeau, S. J. McIlwain, E. Contreras Guzman, K. Nadiminti, A. Hudson, N. S. Callander, M. C. Skala, J. E. Gumperz, P. Hematti, C. M. Capitini

This study identifies CD4+/CD8+ double positive T cells as mediators of xenogeneic GVHD but with limited GVL activity.

bioRxiv · Jan 11, 2022Immunology

MHC-matched allogeneic bone marrow transplant fails to eliminate SHIV-infected cells from ART-suppressed Mauritian cynomolgus macaques

J. T. Weinfurter, S. S. D'Souza, L. M. Matschke, S. Bennett, L. E. Kelnhofer-Millevolte, K. Suknuntha, A. Kumar, J. Coonen, C. M. Capitini, P. Hematti, T. G. Golos, I. I. Slukvin, M. R. Reynolds

This study shows that MHC-matched allogeneic bone marrow transplants in ART-suppressed SHIV-infected macaques do not fully eliminate viral reservoirs, with persistent SHIV DNA in tissues and rebound after ART interruption.

bioRxiv · Apr 16, 2021 · PreprintImmunology

Versican Proteolysis Predicts Immune Effector Infiltration And Post-Transplant Survival In Myeloma

B. Dhakal, A. Pagenkopf, M. U. Mushtaq, A. M. Cunningham, E. Flietner, Z. Morrow, A. Papadas, C. Hope, C. Leith, P. Hematti, P. Hari, N. S. Callander, F. Asimakopoulos

This study shows that VCAN proteolysis predicts CD8+ T cell infiltration and poor survival after myeloma transplantation, suggesting it as a biomarker for relapse risk.

bioRxiv · Sep 12, 2018Immunology