An FcRn-targeted mucosal vaccine against SARS-CoV-2 infection and transmission
W. Li, T. Wang, A. Mekhemadhom Rajendrakumar, G. Acharya, Z. Miao, B. P. Varghese, H. Yu, B. Dhakal, T. LeRoith, W. Tuo, X. Zhu
This study develops an FcRn-targeted mucosal vaccine that reduces SARS-CoV-2 infection and transmission in mice and hamsters by inducing protective immune responses in the airways.
bioRxiv · Nov 23, 2022Immunology