ImmunologybioRxiv
Greater breadth of vaccine-induced immunity in females than males is mediated by increased antibody diversity in germinal center B cells
R. L. Ursin, S. Dhakal, H. Liu…·S. L. Klein
This study shows that female mice have stronger and more diverse antibody responses to influenza vaccination, leading to better protection against mutant viruses due to increased germinal center B cell activity.
DOI 10.1128/mbio.01839-22