Author

H.-S. Park

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Microbiology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 7 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 4 Research Focus:differential expression· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Organism:human· 2

Frequent Co-Authors

C. Luongo· 2 shared C. Santos· 2 shared J.-H. Yu· 2 shared L. Yang· 2 shared P. Lusso· 2 shared P. Zhang· 2 shared R. W. Maul· 2 shared S. Dhakal· 2 shared

Activity by Year

2019-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersMicrobiology

C. Luongo

Mutual co-authors in cluster

Author profile →

8 papers

Recent·Most cited

Estradiol Mediates Greater Germinal Center Responses to Influenza Vaccination in Female than Male Mice

S. Dhakal, H.-S. Park, K. Seddu, J. Lee, P. S. Creisher, K. M. Davis, I. R. Hernandez, R. W. Maul, S. L. Klein

This study shows estradiol enhances germinal center responses and antibody production in female mice after influenza vaccination, leading to better protection against viral challenge.

bioRxiv · Nov 27, 2023Immunology

Live-attenuated pediatric parainfluenza vaccine expressing 6P-stabilized SARS-CoV-2 spike protein is protective against SARS-CoV-2 variants in hamsters

X. Liu, H.-S. Park, Y. Matsuoka, C. Santos, L. Yang, C. Luongo, I. Moore, R. Johnson, N. Garza, P. Zhang, P. Lusso, S. Best, U. Buchholz, C. Le Nouën

This study compares two live-attenuated vaccines in hamsters, showing that B/HPIV3/S-6P induces stronger immune responses and better protection against SARS-CoV-2 variants than B/HPIV3/S-2P.

PLOS Pathogens · Jun 23, 2023Peer-reviewedMicrobiology

The novel spore-specific regulator SscA governs Aspergillus conidiogenesis.

Y.-E. Son, J.-H. Yu, H.-S. Park

This study identifies SscA as a spore-specific transcription factor that regulates conidial formation, integrity, and function in Aspergillus species through transcriptomic analyses.

bioRxiv · May 24, 2023 · PreprintMicrobiology

Greater breadth of vaccine-induced immunity in females than males is mediated by increased antibody diversity in germinal center B cells

R. L. Ursin, S. Dhakal, H. Liu, S. Jayaraman, H.-S. Park, H. R. Powell, M. L. Sherer, K. E. Littlefield, A. L. Fink, Z. Ma, A. L. Mueller, A. P. Chen, Y. A. Woldetsadik, P. J. Gearhart, H. B. Larman, , S. L. Klein

This study shows that female mice have stronger and more diverse antibody responses to influenza vaccination, leading to better protection against mutant viruses due to increased germinal center B cell activity.

bioRxiv · May 31, 2022Immunology

Intranasal pediatric parainfluenza virus-vectored SARS-CoV-2 vaccine candidate is protective in macaques

C. Le Nouen, C. E. Nelson, X. Liu, H.-S. Park, Y. Matsuoka, C. Luongo, C. Santos, L. Yang, R. Herbert, A. Castens, I. N. Moore, T. Wilder-Kofie, R. Moore, A. Walker, P. Zhang, , U. J. Buchholz

This study evaluates an intranasal parainfluenza virus-vectored SARS-CoV-2 vaccine in macaques, showing it induces mucosal and systemic immunity and protects against viral challenge.

bioRxiv · May 21, 2022Immunology

Transcriptomic, protein-DNA interaction, and metabolomic studies of VosA, VelB, and WetA in Aspergillus nidulans asexual spores

M.-Y. Wu, M. E. Mead, M.-K. Lee, G. F. Neuhaus, D. A. Adpressa, J. I. Martien, Y.-E. Son, H. Moon, D. Amador-Noguez, K.-H. Han, A. Rokas, S. Loesgen, J.-H. Yu, H.-S. Park

The paper investigates the regulatory roles of VosA, VelB, and WetA in asexual spore formation in Aspergillus nidulans using transcriptomic, protein-DNA interaction, and metabolomic analyses.

bioRxiv · Sep 9, 2020Microbiology

ARP-T1 is a ciliogenesis protein associated with a novel ciliopathy in inherited basal cell cancer, Bazex-Dupre-Christol Syndrome

H.-S. Park, E. Papanastasi, G. Blanchard, E. Chiticariu, D. Bachmann, M. Plomann, F. Morice-Picard, P. Vabres, A. Smahi, M. Huber, C. Pich, D. Hohl

This study identifies ARP-T1 as a ciliogenesis protein whose mutations cause Bazex-Dupre-Christol Syndrome, linking it to ciliopathy and skin cancer.

bioRxiv · Dec 16, 2019 · PreprintCancer Biology

Medroxyprogesterone reverses tolerable dose metformin-induced inhibition of invasion via matrix metallopeptidase-9 and transforming growth factor-β1 in KLE endometrial cancer cells

D. H. Suh, S. Lee, H.-S. Park, N. H. Park

This study shows that medroxyprogesterone reverses metformin's anti-invasive effect in KLE endometrial cancer cells via MMP-9 and TGF-β1.

bioRxiv · Apr 2, 2019Cancer Biology