Author

P. J. Lewis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

A. C. Pradhan· 1 shared A. J. Oakley· 1 shared A. T. Y. Lo· 1 shared C. G. de Koster· 1 shared E. A. de Koning· 1 shared G. L. Corthals· 1 shared G. Tolun· 1 shared H. Buncherd· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBiochemistry

A. C. Pradhan

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Author profile →

2 papers

Recent·Most cited

Structural characterisation of the complete cycle of sliding clamp loading in Escherichia coli

Z.-Q. Xu, S. Jergic, A. T. Y. Lo, A. C. Pradhan, S. H. J. Brown, J. C. Bouwer, H. Ghodke, P. J. Lewis, G. Tolun, A. J. Oakley, N. E. Dixon

This study presents six high-resolution structures of the E. coli clamp loader complex (CLC) during the clamp loading process, revealing the molecular mechanism of clamp opening and DNA binding.

bioRxiv · Jul 20, 2023 · PreprintBiochemistry

In culture cross-linking of bacterial cells reveals proteome scale dynamic protein-protein interactions at the peptide level

L. de Jong, E. A. de Koning, W. Roseboom, H. Buncherd, M. J. Wanner, P. J. Jansen, I. Dapic, J. H. van Maarseveen, G. L. Corthals, P. J. Lewis, L. W. Hamoen, C. G. de Koster

The paper develops a method to identify dynamic protein-protein interactions at the peptide level in bacteria using cross-linking in culture, revealing new interactions in transcription and translation.

Journal of Proteome Research · Jul 7, 2017Peer-reviewedBiochemistry