Author

S. H. J. Brown

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:protein structure prediction· 2 Organism:E. coli· 1 Assay:metabolomics· 1 Organism:plant (other)· 1 Assay:protein structure· 1

Frequent Co-Authors

A. J. Oakley· 2 shared A. C. Pradhan· 1 shared A. E. Whitten· 1 shared A. G. Maier· 1 shared A. G. Stewart· 1 shared A. Kelleher· 1 shared A. T. Y. Lo· 1 shared B. Garner· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

A. J. Oakley

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Structural characterisation of the complete cycle of sliding clamp loading in Escherichia coli

Z.-Q. Xu, S. Jergic, A. T. Y. Lo, A. C. Pradhan, S. H. J. Brown, J. C. Bouwer, H. Ghodke, P. J. Lewis, G. Tolun, A. J. Oakley, N. E. Dixon

This study presents six high-resolution structures of the E. coli clamp loader complex (CLC) during the clamp loading process, revealing the molecular mechanism of clamp opening and DNA binding.

bioRxiv · Jul 20, 2023 · PreprintBiochemistry

Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients

R. Rouet, J. Y. Henry, M. D. Johansen, M. Sobti, H. Balachandran, D. B. Langley, G. Walker, H. Lenthall, J. Jackson, S. Ubiparipovic, O. Mazigi, P. Schofield, D. L. Burnett, S. H. J. Brown, M. Martinello, , D. Christ

This paper isolates broadly neutralizing SARS-CoV-2 antibodies from convalescent patients and shows they neutralize emerging variants more effectively than existing monoclonal antibodies.

bioRxiv · Oct 19, 2022Immunology

Analysis of sex-specific lipid metabolism in P. falciparum gametocytes points to importance of sphingomyelin for gametocytogenesis

M. C. Ridgway, D. Cihalova, S. H. J. Brown, P. Tran, T. W. Mitchell, A. G. Maier

This study identifies sex-specific lipid differences in Plasmodium falciparum gametocytes, showing sphingomyelin is critical for gametocytogenesis while cholesteryl esters are not.

bioRxiv · Nov 2, 2021Microbiology

Identification of a novel tetrameric structure for human apolipoprotein-D

C. S. Kielkopf, J. K. K. Low, Y.-F. Mok, S. Bhatia, T. Palasovski, A. J. Oakley, A. E. Whitten, B. Garner, S. H. J. Brown

This study identifies a tetrameric structure of human apolipoprotein-D in breast cyst fluid, contrasting with its monomeric or higher-order forms in other biological fluids.

bioRxiv · May 31, 2018Biochemistry