L. W. Hamoen

Divisome minimization shows that FtsZ and SepF can form an active Z-ring, and reveals BraB as a new cell division influencing protein in Bacillus subtilis

This study identifies FtsZ and SepF as essential for Z-ring formation in Bacillus subtilis and discovers BraB as a new cell division regulator through gene deletion experiments.

The conserved protein WhiA influences branched-chain fatty acid precursors in Bacillus subtilis

This study investigates the function of WhiA in B. subtilis using yeast two-hybrid, Hi-C, metabolomics, and transcriptomics, finding reduced branched-chain fatty acid precursors in ΔwhiA cells.

Time-lapse imaging of bacterial morphology facilitates classification of antimicrobial agents

The paper introduces a time-lapse imaging method to classify antimicrobial agents based on their effects on bacterial morphology.

Different resource allocation in a Bacillus subtilis population displaying bimodal motility

This study compares gene expression between motile and non-motile cells in Bacillus subtilis, finding reduced ribosomal gene expression in motile cells, suggesting resource reallocation to motility systems.

Control of septum thickness by a large protein ring

This study shows that SepF protein rings in bacteria control septal thickness, with ring diameter correlating to septum thickness and manipulation of ring size altering septum thickness.

New flat embedding method for transmission electron microscopy reveals an unknown mechanism of tetracycline

This paper introduces a new flat embedding method for TEM that enables large-scale quantification of bacterial morphological changes, revealing tetracycline's previously unknown membrane-disrupting activity.

Membrane curvature and the Tol-Pal complex determine polar localization of the chemoreceptor Tar in E. coli

This study identifies membrane curvature and Tol-Pal complex interaction as key factors for polar localization of the chemoreceptor Tar in E. coli.

In culture cross-linking of bacterial cells reveals proteome scale dynamic protein-protein interactions at the peptide level

The paper develops a method to identify dynamic protein-protein interactions at the peptide level in bacteria using cross-linking in culture, revealing new interactions in transcription and translation.