Aged-senescent cells contribute to impaired heart regeneration
F. C. Lewis-McDougall, P. J. Ruchaya, E. Domenjo-Vila, T. S. Teoh, L. Prata, B. J. Cottle, J. E. Clark, P. P. Punjabi, W. Awad, D. Torella, T. Tchkonia, J. L. Kirkland, G. M. Ellison-Hughes
This study shows that aged-senescent cardiac progenitor cells impair heart regeneration and that eliminating them improves cardiac function in aged mice.
bioRxiv · Oct 1, 2018Physiology