Author

P. Jakobs

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

A. Bogorodskiy· 1 shared A. Katranidis· 1 shared A. Mishin· 1 shared A. Schulga· 1 shared D. Burkatovskiy· 1 shared D. Manikowski· 1 shared F. Gude· 1 shared F. von Ameln· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCell Biology

A. Bogorodskiy

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2 papers

Recent·Most cited

Conserved cholesterol-related activities of Dispatched drive Sonic hedgehog shedding from the cell membrane

K. Grobe, K. Ehring, D. Manikowski, J. Froese, P. Jakobs, F. Gude, U. Rescher, J. Goretzko

This study shows that Dispatched (Disp) facilitates cholesterol-dependent ectodomain shedding of Sonic hedgehog (Shh) ligand, and that this process is rescued by cholesterol removal or overexpression of Disp or Patched.

bioRxiv · Oct 19, 2020Cell Biology

Accessing mitochondrial protein import in living cells by protein microinjection

A. Bogorodskiy, I. Okhrimenko, I. Maslov, N. Maliar, D. Burkatovskiy, F. von Ameln, A. Schulga, P. Jakobs, J. Altschmied, J. Haendeler, A. Katranidis, A. Mishin, V. Gordeliy, G. Bueldt, W. Voos, , V. Borshchevskiy

This study develops a microinjection method to study mitochondrial protein import in living cells and finds that puromycin enhances import rates by releasing nascent polypeptides from ribosomes.

bioRxiv · Sep 30, 2020Cell Biology