I. Maslov

Angiotensin-(1-5) is a Potent Endogenous Angiotensin AT2-Receptor Agonist

This study identifies angiotensin-(1-5) as a potent endogenous agonist of the AT2-receptor, showing its ability to increase nitric oxide release and lower blood pressure through AT2R-mediated mechanisms.

Functional GPCR expression in eukaryotic LEXSY system

The paper compares GPCR expression in the LEXSY eukaryotic system to insect cells, finding higher protein yield in LEXSY for the A2A adenosine receptor.

Monitoring GPCR Conformation with GFP-Inspired Dyes

This study develops GFP-inspired dyes to monitor ligand-induced conformational changes in GPCRs, showing fluorescence responses to agonists and allosteric modulators.

Revealing the Oligomerization of Channelrhodopsin-2 in the Cell Membrane using Photo-Activated Localization Microscopy

This study uses qPALM to show ChR2 predominantly forms dimers in the cell membrane, with disulfide bonds not essential for dimerization and partial monomerization observed at low concentrations.

Sub-millisecond conformational dynamics of the A2A adenosine receptor revealed by single-molecule FRET

This study uses smFRET to analyze the conformational dynamics of the A2A adenosine receptor, revealing slow and fast dynamics in different ligand-bound states.

Accessing mitochondrial protein import in living cells by protein microinjection

This study develops a microinjection method to study mitochondrial protein import in living cells and finds that puromycin enhances import rates by releasing nascent polypeptides from ribosomes.

Metabolic fate of human immunoactive sterols in Mycobacterium tuberculosis

The paper identifies Mtb enzymes that metabolize human immune oxysterols and vitamin D3 derivatives, revealing a potential drug target for tuberculosis treatment.