Author

P. K. Zuber

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

S. H. Knauer· 3 shared I. Artsimovitch· 2 shared K. Schweimer· 2 shared B. Loll· 1 shared B. Wang· 1 shared C. A. Ramirez-Sarmiento· 1 shared G. A. Belogurov· 1 shared J. Gonzlez-Higueras· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBiochemistry

S. H. Knauer

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3 papers

Recent·Most cited

Concerted transformation of a hyper-paused transcription complex and its reinforcing protein

P. K. Zuber, N. Said, T. Hilal, B. Wang, B. Loll, J. Gonzlez-Higueras, C. A. Ramirez-Sarmiento, G. A. Belogurov, I. Artsimovitch, M. Wahl, S. H. Knauer

This paper reveals how RfaH activates virulence gene expression by transforming its structure and stabilizing paused transcription complexes through interactions with ops hairpins.

bioRxiv · Jun 26, 2023Biochemistry

Structural and thermodynamic analyses of the β-to-α transformation in RfaH reveal principles of fold-switching proteins

P. K. Zuber, T. Daviter, R. Heissmann, U. Persau, K. Schweimer, S. H. Knauer

This study analyzes the structural and thermodynamic properties of RfaH and NusG/Spt5-KOW domains to understand the mechanisms of fold-switching in proteins.

bioRxiv · Jan 14, 2022Biophysics

The universally-conserved transcription factor RfaH is recruited to a hairpin structure of the non-template DNA strand

P. K. Zuber, I. Artsimovitch, M. NandyMazumdar, Z. Liu, Y. Nedialkov, K. Schweimer, P. Roesch, S. H. Knauer

The paper shows RfaH, a transcription factor, binds to a hairpin structure in the non-template DNA strand via a conserved pause sequence, revealing a new mechanism for transcriptional regulation.

bioRxiv · Apr 26, 2018Biochemistry