Selective Nanotherapeutic Targeting of the Neutrophil Subset Mediating Inflammatory Injury
K. Bachmaier, A. Stuart, Z. Hong, Y. Tsukasaki, A. Singh, S. Chakraborty, A. Mukhopadhyay, X. Gao, M. Maienschein-Cline, P. Kanteti, R. Rehman, A. B. Malik
This study identifies a neutrophil subset responsible for ALI in sepsis and shows that targeting it with nanotherapeutics prevents ALI without harming host defense.
bioRxiv · Jun 30, 2020 · PreprintImmunology