Author

P. L. Davies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 3 Organism:human· 2 Assay:protein structure· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

L. A. Graham· 2 shared A. Henrickson· 1 shared B. Demeler· 1 shared C. L. Scholl· 1 shared G. Ovadia· 1 shared H. E. Tomalty· 1 shared I. Braslavsky· 1 shared J. C. Lee· 1 shared

Activity by Year

2021-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersCell Biology

L. A. Graham

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Human calpain-3 and its structural plasticity: dissociation of a homohexamer into dimers on binding titin

Q. Ye, A. Henrickson, B. Demeler, V. H. Serrao, P. L. Davies

This study investigates the structural plasticity of calpain-3, showing it forms a hexamer that dissociates into dimers upon binding titin.

bioRxiv · Feb 28, 2024Biochemistry

Ice nucleation proteins self-assemble into large fibres to trigger freezing at near 0 ℃

T. Hansen, J. C. Lee, N. Reicher, G. Ovadia, S. Guo, W. Guo, J. Liu, I. Braslavsky, Y. Rudich, P. L. Davies

The paper shows ice nucleation proteins self-assemble into fibres that trigger freezing near 0 ℃ by forming multimers essential for frost formation.

bioRxiv · Aug 3, 2023Biochemistry

Protein engineering shows antifreeze activity scales with ice-binding site area

C. L. Scholl, P. L. Davies

The paper shows that increasing the ice-binding site (IBS) area of an antifreeze protein enhances its antifreeze activity, while reducing area decreases activity.

bioRxiv · Sep 7, 2022 · PreprintBiochemistry

Chill injury in human kidney tubule cells after subzero storage is not mitigated by antifreeze protein addition

H. E. Tomalty, L. A. Graham, V. K. Walker, P. L. Davies

The paper assesses whether antifreeze proteins mitigate chill injury in human kidney tubule cells during subzero storage, finding no benefit despite reduced freezing.

bioRxiv · Aug 9, 2022 · PreprintCell Biology

Origin of the type I antifreeze gene in flounders in response to Cenozoic climate change

L. A. Graham, S. Y. Gauthier, P. L. Davies

This study traces the origin of type I antifreeze genes in flounders, showing they evolved from Gig2 genes and expanded during Cenozoic cooling.

bioRxiv · Sep 21, 2021 · PreprintEvolutionary Biology