Author

P. M. Fraczek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:ATAC-seq· 2 Assay:bulk RNA-seq· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2

Frequent Co-Authors

B. A. Yang· 4 shared C. A. Aguilar· 4 shared J. A. Larouche· 3 shared S. V. Brooks· 2 shared A. Monteiro da Rocha· 1 shared A. Shcherbina· 1 shared B. M. Baker· 1 shared C. Davis· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersCell Biology

B. A. Yang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell BiologybioRxivMar 12, 2023

Manipulation of the nucleoscaffold potentiates cellular reprogramming kinetics

B. A. Yang, A. Monteiro da Rocha, I. Newton…·C. A. Aguilar

This study shows that manipulating Lamin A/C affects nuclear structure and reprogramming efficiency in human fibroblasts.

DOI 10.1093/pnasnexus/pgaf307

𝕏 PostBluesky

Cell BiologybioRxivSep 21, 2022

Three-dimensional chromatin re-organization during muscle stem cell aging

B. A. Yang, J. A. Larouche, K. M. Sabin…·C. A. Aguilar

This study examines how 3D chromatin organization changes in muscle stem cells during aging, revealing static global structures and rewired local contacts linked to transcription factor binding and gene expression changes.

DOI 10.1111/acel.13789

𝕏 PostBluesky

Cell BiologybioRxivJul 2, 2021

Neutrophil and natural killer cell imbalances prevent muscle stem cell mediated regeneration following murine volumetric muscle loss

J. A. Larouche, S. J. Kurpiers, B. A. Yang…·C. A. Aguilar

The study compares muscle injuries leading to regeneration or fibrosis, revealing that neutrophil-natural killer cell communication affects muscle stem cell repair.

DOI 10.1073/pnas.2111445119

mousebulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivDec 15, 2020

Sestrins regulate age-induced deterioration of muscle stem cell homeostasis

B. A. Yang, J. A. Castor-Macias, P. M. Fraczek…·C. A. Aguilar

This study shows that Sestrins maintain muscle stem cell quiescence and function by regulating mTORC1 signaling and metabolism, and their loss accelerates age-related deterioration.

DOI 10.1016/j.stemcr.2021.07.014

mouseexperimental assay

𝕏 PostBluesky