Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
11 papers
Recent·Most cited
E. D. Buras, M.-S. Woo, R. K. Verma, S. H. Kondisetti, C. S. Davis, D. R. Claflin, K. Converso-Baran, D. E. Michele, S. V. Brooks, T.-H. Chun
This study shows that THBS1 promotes diaphragm stromal expansion and contractile dysfunction in obesity by driving FAP proliferation and ECM changes.
bioRxiv · Aug 17, 2023Cell Biology
J. A. Castor-Macias, J. A. Larouche, E. C. Wallace, B. D. Spence, A. Eames, B. A. Yang, C. Davis, S. V. Brooks, K. R. Maddipati, J. F. Markworth, C. A. Aguilar
This study shows that Maresin 1 treatment reduces fibrosis and improves muscle regeneration after volumetric muscle loss by modulating inflammation.
bioRxiv · Nov 19, 2022Physiology
N. Pollock, P. C. Macpherson, C. A. Staunton, K. Hemmings, C. S. Davis, E. D. Owen, A. Vasilaki, H. Van Remmen, A. Richardson, A. McArdle, S. V. Brooks, M. J. Jackson
This study shows that deleting Sod1 in motor neurons worsens age-related muscle atrophy and NMJ changes in old mice, but not in younger mice.
bioRxiv · Jan 27, 2022 · PreprintPhysiology
J. A. Larouche, S. J. Kurpiers, B. A. Yang, C. Davis, P. M. Fraczek, M. Hall, S. V. Brooks, L. D. Shea, C. A. Aguilar
The study compares muscle injuries leading to regeneration or fibrosis, revealing that neutrophil-natural killer cell communication affects muscle stem cell repair.
bioRxiv · Jul 2, 2021Cell Biology
J. F. Markworth, K. B. Sugg, D. C. Sarver, K. R. Maddipati, S. V. Brooks
This study identifies delayed and prolonged inflammatory responses in overused tendons, marked by elevated pro-inflammatory eicosanoids and reduced pro-resolving lipid mediators.
bioRxiv · Jan 8, 2021Immunology
B. A. Yang, J. A. Castor-Macias, P. M. Fraczek, L. A. Brown, M. Kim, S. V. Brooks, J. H. Lee, C. A. Aguilar
This study shows that Sestrins maintain muscle stem cell quiescence and function by regulating mTORC1 signaling and metabolism, and their loss accelerates age-related deterioration.
bioRxiv · Dec 15, 2020Cell Biology
J. F. Markworth, L. A. Brown, E. Lim, J. A. Castor-Macias, J. Larouche, P. C. D. Macpherson, C. Davis, C. A. Aguilar, K. R. Maddipati, S. V. Brooks
This study identifies age-related deficiencies in proresolving mediators in skeletal muscle, leading to impaired regeneration and inflammation, and shows that RvD1 treatment can mitigate some adverse effects.
bioRxiv · Nov 5, 2020Immunology
L. C. Gunder, I. Harvey, J. R. Redd, C. S. Davis, A. AL-Tamimi, S. V. Brooks, D. Bridges
This study shows that obesity in mice enhances glucocorticoid-induced muscle atrophy by increasing atrogene expression and reducing muscle strength.
bioRxiv · Aug 11, 2020Physiology
J. F. Markworth, L. A. Brown, E. Lim, C. Floyd, J. Larouche, J. A. Castor-Macias, K. B. Sugg, D. C. Sarver, P. C. F. Macpherson, C. Davis, C. A. Aguilar, K. R. Maddipati, S. V. Brooks
This study shows that resolvin D1 promotes skeletal muscle regeneration by modulating myeloid cells and muscle stem cells, improving recovery without directly affecting myogenesis.
bioRxiv · Jun 12, 2020Immunology
P. J. Ulintz, J. Larouche, M. Mohiuddin, J. Castor Macias, S. J. Kurpiers, W. Liu, J. J. Choi, L. A. Brown, J. F. Markworth, K. de Silva, B. D. Levi, S. D. Merajver, J. V. Chakkalakal, Y. C. Jang, S. V. Brooks, C. A. Aguilar
The paper identifies a neuro-responsive subset of muscle stem cells that support neuromuscular junction integrity during aging and neurodegeneration.
bioRxiv · May 28, 2020Cell Biology
K. B. Sugg, J. F. Markworth, N. P. Disser, A. M. Rizzi, J. R. Talarek, D. C. Sarver, S. V. Brooks, C. L. Mendias
This study shows PDGFR signaling is essential for postnatal tendon growth and remodeling, with MT1-MMP mediating fibroblast migration and being regulated by PI3K/Akt and ERK1/2.
bioRxiv · Oct 25, 2017Physiology