Author

P. McAlpine

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Cell Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

D. S. You· 1 shared E. Zatulovskiy· 1 shared G. K. Marinov· 1 shared I. Ilerten· 1 shared J. E. Elias· 1 shared J. M. Skotheim· 1 shared L. Zhang· 1 shared M. C. Lanz· 1 shared

Activity by Year

2021-2021 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

D. S. You

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1 paper

Recent·Most cited

Increasing cell size remodels the proteome and promotes senescence

M. C. Lanz, E. Zatulovskiy, M. P. Swaffer, L. Zhang, I. Ilerten, S. Zhang, D. S. You, G. K. Marinov, P. McAlpine, J. E. Elias, J. M. Skotheim

The paper shows that increasing cell size remodels the proteome and promotes senescence, but polyploidization can prevent this by altering the DNA-to-ploidy ratio.

bioRxiv · Jul 29, 2021Cell Biology