Oxidative stress potentiates the therapeutic action of a mitochondrial complex I inhibitor in MYC-driven B-cell lymphoma
G. Donati, P. Nicoli, A. Verrecchia, V. Vallelonga, O. Croci, S. Rodighiero, M. Audano, L. Cassina, A. Ghsein, G. Binelli, A. Boletta, N. Mitro, B. Amati
This study shows that combining a mitochondrial complex I inhibitor with oxidative stress inducers enhances the killing of MYC-driven lymphoma cells.
bioRxiv · Jun 21, 2022 · PreprintCancer Biology