Overcoming Resolution Attenuation During Tilted Cryo-EM Data Collection
S. Aiyer, P. R. Baldwin, S. M. Tan, Z. Shan, J. Oh, A. Mehrani, M. E. Bowman, G. Louie, D. O. Passos, S. Đorđevic-Marquardt, M. Mietzsch, J. A. Hull, S. Hoshika, B. A. Barad, D. Grotjahn, , D. Lyumkis
This study improves cryo-EM data collection by reducing resolution attenuation during stage tilt, enabling isotropic map reconstruction of specimens with preferred orientations.
bioRxiv · Jul 14, 2023Biophysics