Author

D. O. Passos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Assay:cryo-EM· 2 Approach:experimental assay· 2 Research Focus:protein structure prediction· 2 Organism:bacteria (other)· 1 Organism:human· 1

Frequent Co-Authors

D. Lyumkis· 2 shared A. Mehrani· 1 shared B. A. Barad· 1 shared D. Grotjahn· 1 shared D. Wang· 1 shared E. Arnold· 1 shared F. X. Ruiz· 1 shared G. Louie· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersBiophysics

D. Lyumkis

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2 papers

Recent·Most cited

Overcoming Resolution Attenuation During Tilted Cryo-EM Data Collection

S. Aiyer, P. R. Baldwin, S. M. Tan, Z. Shan, J. Oh, A. Mehrani, M. E. Bowman, G. Louie, D. O. Passos, S. Đorđevic-Marquardt, M. Mietzsch, J. A. Hull, S. Hoshika, B. A. Barad, D. Grotjahn, , D. Lyumkis

This study improves cryo-EM data collection by reducing resolution attenuation during stage tilt, enabling isotropic map reconstruction of specimens with preferred orientations.

bioRxiv · Jul 14, 2023Biophysics

Cryo-EM Structure of the Pol Polyprotein Provides Insights into HIV Maturation

J. J. E. K. Harrison, D. O. Passos, J. F. Bruhn, J. D. Bauman, L. Tuberty, J. J. DeStefano, F. X. Ruiz, D. Lyumkis, E. Arnold

The paper determines the cryo-EM structure of the HIV-1 Pol polyprotein intermediate, revealing how RT dimerization activates proteolytic processing by bringing PR monomers together.

bioRxiv · Oct 3, 2021 · PreprintBiophysics