Author

V. Rajeeve

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

P. Cutillas· 4 shared T. D. Nightingale· 2 shared A. Agrotis· 1 shared A. Barker· 1 shared A. D. Dokal· 1 shared A. Nagano· 1 shared A. White· 1 shared B. Yaman· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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4 shared papersCancer Biology

P. Cutillas

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Extracellular matrix educates a tumor macrophage phenotype found in ovarian cancer metastasis

E. H. Puttock, E. J. Tyler, M. Manni, E. Maniati, C. Butterworth, E. Peerani, P. Hirani, V. Gauthier, Y. Liu, G. Maniscalco, V. Rajeeve, P. Cutillas, C. Trevisan, M. Pozzobon, M. Lockley, , O. M. T. Pearce

The paper shows that the tumor extracellular matrix educates macrophages to adopt a phenotype seen in ovarian cancer metastasis, affecting T cell function and immune regulation.

bioRxiv · Aug 11, 2022 · PreprintCancer Biology

Proximity interactome of LC3B in normal growth conditions

M. Nollet, A. Agrotis, F. Michailidis, A. D. Dokal, V. Rajeeve, J. Burden, T. D. Nightingale, P. Cutillas, R. Ketteler, S. Kermorgant

The paper identifies 407 proteins interacting with LC3B in normal growth conditions using APEX2 proteomics, revealing novel interactors and expanding understanding of LC3B's roles beyond autophagy.

bioRxiv · Oct 8, 2021 · PreprintCell Biology

The breast cancer oncogene IKKε coordinates mitochondrial function and serine metabolism

R. Xu, W. Jones, E. Wilcz-Villega, S. Costa, V. Rajeeve, R. B. Bentham, K. Bryson, A. Nagano, B. Yaman, S. Olendo Barasa, Y. Wang, C. Chelala, P. Cutillas, G. Szabadkai, C. Frezza, K. Bianchi

This study shows that IKKε, a breast cancer oncogene, reprograms mitochondrial function and serine metabolism independently of its canonical signaling role, promoting cancer cell proliferation.

bioRxiv · Nov 26, 2019Cancer Biology

Dynamic trafficking and turnover of Jam-C is essential for endothelial cell migration

K. B. Kostelnik, A. Barker, C. Schultz, V. Rajeeve, I. J. White, M. Aurrand-Lions, S. Nourshargh, P. Cutillas, T. D. Nightingale

The paper identifies Jam-C trafficking and ubiquitylation by CBL as essential for endothelial cell migration and junctional remodelling during angiogenesis.

bioRxiv · Jul 12, 2019Cell Biology

Global analysis of specificity determinants in eukaryotic protein kinases

D. Bradley, C. Vieitez, V. Rajeeve, P. R. Cutillas, P. Beltrao

The paper identifies 30 putative specificity determinant residues in protein kinases and shows their conservation and mutation patterns in cancer and evolution.

bioRxiv · Aug 20, 2018Cell Biology