Distinct functions of EHMT1 and EHMT2 in cancer chemotherapy and immunotherapy
Z. Kang, P. Fu, H. Ma, T. Li, K. Lu, J. Liu, V. Ginjala, P. Romanienko, Z. Feng, M. Guan, S. Ganesan, B. Xia
This study shows EHMT1 and EHMT2 have distinct roles in cancer therapy, with EHMT1 affecting DNA replication and alkylating agents, while EHMT2 influences immunotherapy response via STING expression.
bioRxiv · Oct 3, 2023 · PreprintCancer Biology