Author

P. s. Ellis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:zebrafish· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

A. Farhat· 1 shared C. A. Loynes· 1 shared C. Henriques· 1 shared C. M. Henriques· 1 shared E. Thompson· 1 shared H. J. Mortiboys· 1 shared I. Bellantuono· 1 shared R. R. Martins· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

A. Farhat

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2 papers

Recent·Most cited

A p21-GFP zebrafish model of senescence for rapid testing of senolytics in vivo.

S. Morsli, C. Henriques, P. s. Ellis, H. J. Mortiboys, S. Baxendale, C. A. Loynes, S. Renshaw, I. Bellantuono

This paper develops a zebrafish model expressing p21-GFP to study senescence and test senolytics, showing that quercetin and dasatinib reduce senescent cells in a 5-day assay.

bioRxiv · Sep 19, 2022Pharmacology & Toxicology

A subset of gut leukocytes have telomerase-dependent 'hyper-long' telomeres and require telomerase for function in zebrafish

P. S. Ellis, R. R. Martins, E. Thompson, A. Farhat, S. A. Renshaw, C. M. Henriques

This paper shows that telomerase-dependent 'hyper-long' telomeres in zebrafish gut macrophages and dendritic cells decline with age, leading to impaired immunity and increased gut permeability.

bioRxiv · Jan 31, 2022Cell Biology