Author

I. Bellantuono

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 2 Research Focus:cancer & tumor microenvironment· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1

Frequent Co-Authors

A. Arroquia-Soriano· 1 shared B. McDonagh· 1 shared C. A. Loynes· 1 shared C. Henriques· 1 shared C. Slack· 1 shared D. Bardell· 1 shared E. McCloskey· 1 shared H. J. Mortiboys· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

A. Arroquia-Soriano

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A p21-GFP zebrafish model of senescence for rapid testing of senolytics in vivo.

S. Morsli, C. Henriques, P. s. Ellis, H. J. Mortiboys, S. Baxendale, C. A. Loynes, S. Renshaw, I. Bellantuono

This paper develops a zebrafish model expressing p21-GFP to study senescence and test senolytics, showing that quercetin and dasatinib reduce senescent cells in a 5-day assay.

bioRxiv · Sep 19, 2022Pharmacology & Toxicology

miR-24:Prdx6 interactions regulate oxidative stress and viability of myogenic progenitors during ageing

K. Goljanek-Whysall, A. Arroquia-Soriano, J. Gostage, D. Bardell, E. McCloskey, I. Bellantuono, P. D. Clegg, B. McDonagh

This study shows miR-24-3p and its target Prdx6 regulate oxidative stress and viability of myogenic progenitors during ageing, with miR-24 downregulation in old mice linked to increased ROS and satellite cell senescence.

bioRxiv · Jan 25, 2021 · PreprintCell Biology

Zoledronate extends healthspan and survival via the mevalonate pathway in a FOXO-dependent manner

Z. Chen, J. Cordero, C. Slack, M. P. Zeidler, I. Bellantuono

This study shows zoledronate extends lifespan and healthspan in Drosophila by modulating the mevalonate pathway through FOXO-dependent mechanisms.

bioRxiv · Apr 9, 2020Pharmacology & Toxicology