Author

P. S. Merkle

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Biophysics· 1

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Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:structural biology· 1

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C. J. Loland· 1 shared K. D. Rand· 1 shared K. Gotfryd· 1 shared K. Z. Leth-Espensen· 1 shared M. A. Cuendet· 1 shared U. Gether· 1 shared

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2017-2017 · peak 1/yr

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1 shared paperBiophysics

C. J. Loland

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1 paper

Recent·Most cited

BiophysicsbioRxivJun 28, 2017

Partial Unwinding of Transmembrane Helices Facilitates Alternating Access in the Neurotransmitter:Sodium Symporter LeuT

P. S. Merkle, K. Gotfryd, M. A. Cuendet…·K. D. Rand

This paper uses HDX-MS to study LeuT's structural dynamics during substrate translocation, revealing that partial unwinding of transmembrane helices facilitates the transition between outward- and inward-facing states.

DOI 10.1126/sciadv.aar6179

bacteria (other)structural biology

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