Author

K. D. Rand

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:protein folding & dynamics· 3 Assay:proteomics· 2 Assay:structural biology· 2 Organism:bacteria (other)· 1 Research Focus:cell type annotation· 1 Approach:comparative / phylogenetic analysis· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Biolchi· 1 shared A. M. Buckle· 1 shared A. Zeck· 1 shared B. Benucci· 1 shared B. T. Porebski· 1 shared C. F. Reboul· 1 shared C. J. Loland· 1 shared C. Wagner· 1 shared

Activity by Year

2017-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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1 shared paperBiophysics

A. Biolchi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Structure and dynamics of the autoantigen GAD65 in complex with the human autoimmune polyendocrine syndrome type 2-associated autoantibody b96.11

S. Stander, C. F. Reboul, S. N. Lee, D. Williams, P. G. Chandler, M. G. Costa, D. E. Hoke, J. D. Jimma, J. Fodor, G. Fenalti, S. I. Mannering, B. T. Porebski, P. Schofield, D. Christ, M. Buckle, , A. M. Buckle

This study characterizes the structure and dynamics of GAD65 and its interaction with autoantibody b96.11, revealing how intrinsic conformational flexibility drives autoantigenicity.

bioRxiv · Mar 18, 2024 · PreprintBiochemistry

Structural dynamics and immunogenicity of the recombinant and outer membrane vesicle-embedded Meningococcal antigen NadA

V. Calvaresi, L. Dello Iacono, S. Borghi, E. Luzzi, A. Biolchi, B. Benucci, I. Ferlenghi, I. Peschiera, F. Giusti, L. E. Fontana, Z.-Y. Kan, Z. Spinello, M. Merola, I. Delany, K. D. Rand, N. Norais

This study compares the structural dynamics and immunogenicity of recombinant NadA and OMV-embedded NadA, showing that the native form elicits stronger immune responses.

bioRxiv · Jan 30, 2024Biophysics

Development of a PNGase Rc column for online deglycosylation of complex glycoproteins during HDX-MS

T. O. T. Lambert, M. Gramlich, L. S. Stutzke, L. Smith, D. Deng, P. D. Kaiser, U. Rothbauer, J. L. Benesch, C. Wagner, M. Koenig, P. Pompach, P. Novak, A. Zeck, K. D. Rand

The paper develops a PNGase Rc column for online deglycosylation during HDX-MS, enabling efficient analysis of glycoproteins and mapping of mAb binding epitopes.

bioRxiv · Jul 28, 2023Biochemistry

Investigating the conformational response of the Sortilin receptor upon binding endogenous peptide- and protein ligands by HDX-MS

E. Trabjerg, N. Abu-Asad, Z. Wan, F. Kartberg, S. Christensen, K. D. Rand

This study uses HDX-MS to analyze how Sortilin's conformation changes upon binding different endogenous ligands, revealing distinct conformational impacts and a potential link between ligand binding and a remote domain.

bioRxiv · Sep 14, 2018Biophysics

Partial Unwinding of Transmembrane Helices Facilitates Alternating Access in the Neurotransmitter:Sodium Symporter LeuT

P. S. Merkle, K. Gotfryd, M. A. Cuendet, K. Z. Leth-Espensen, U. Gether, C. J. Loland, K. D. Rand

This paper uses HDX-MS to study LeuT's structural dynamics during substrate translocation, revealing that partial unwinding of transmembrane helices facilitates the transition between outward- and inward-facing states.

bioRxiv · Jun 28, 2017Biophysics