Author

P. Seiffert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

B. B. Kragelund· 2 shared K. Lindorff-Larsen· 2 shared A. Petry· 1 shared C. R. Grace· 1 shared E. A. Newcombe· 1 shared E. E. Tranchant· 1 shared F. Pesce· 1 shared G. W. Haxholm· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiophysics

B. B. Kragelund

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2 papers

Recent·Most cited

The prolactin receptor scaffolds Janus kinase 2 via co-structure formation with phosphoinositide-4,5-bisphosphate

R. Araya-Secchi, K. Bugge, P. Seiffert, A. Petry, G. W. Haxholm, K. Lindorff-Larsen, S. F. Pedersen, L. Arleth, B. B. Kragelund

This study shows that the prolactin receptor forms a co-structure with JAK2 and PI(4,5)P2, enabling signal transduction by stabilizing the receptor's disordered domain.

bioRxiv · Nov 23, 2022Biophysics

Assessment of models for calculating the hydrodynamic radius of intrinsically disordered proteins

F. Pesce, E. A. Newcombe, P. Seiffert, E. E. Tranchant, J. G. Olsen, C. R. Grace, B. B. Kragelund, K. Lindorff-Larsen

The paper evaluates models for calculating the hydrodynamic radius of intrinsically disordered proteins using conformational ensembles validated by small-angle X-ray scattering and finds the Kirkwood-Riseman equation to be the most accurate.

bioRxiv · Jun 11, 2022Biophysics