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2 papers
Recent·Most cited
T. Oh, M. Zabalawi, S. Jain, D. Long, P. Stacpoole, C. McCall, M. A. Quinn
This study shows that dichloroacetate improves energy balance and feeding behavior in sepsis by reversing metabolic dysfunctions and glycine deficiency.
bioRxiv · Jul 21, 2021Immunology
R. Mainali, M. Zabalwi, D. Long, N. Buechler, E. Quillen, C.-C. Key, X. Zhu, J. Parks, C. Furdui, P. Stacpoole, J. Martinez, C. E. McCall, M. A. Quinn
This study shows dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction by targeting mitochondrial PDC/PDK energy homeostasis in a mouse model.
eLife · Feb 22, 2021Peer-reviewedImmunology