Author

C. Furdui

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Research Focus:metabolism & bioenergetics· 2 Assay:bulk RNA-seq· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

C.-C. Key· 2 shared J. Parks· 2 shared M. A. Quinn· 2 shared N. Buechler· 2 shared R. Mainali· 2 shared X. Zhu· 2 shared A. Meyers· 1 shared C. E. McCall· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersPhysiology

C.-C. Key

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Itaconate stabilizes CPT1a to enhance lipid utilization during inflammation

R. Mainali, N. Buechler, C. Ortero, L. Edwards, C.-C. Key, C. Furdui, M. A. Quinn

This study shows itaconate stabilizes CPT1a to enhance lipid utilization during inflammation, revealing a novel metabolic role in modulating fatty acid oxidation during sepsis.

bioRxiv · Aug 14, 2023Physiology

Hematopoietic-SLC37A2 deficiency accelerates atherosclerosis in LDL receptor-deficient mice

Q. Zhao, Z. Wang, A. Meyers, J. Madenspacher, M. Zabalawi, E. Boudyguina, F.-C. Hsu, C. McCall, C. Furdui, J. Parks, M. Fessler, X. Zhu

This study shows that hematopoietic SLC37A2 deficiency accelerates atherosclerosis in LDL receptor-deficient mice by impairing anti-inflammatory responses and IL-10 production.

bioRxiv · Aug 6, 2021 · PreprintImmunology

Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction

R. Mainali, M. Zabalwi, D. Long, N. Buechler, E. Quillen, C.-C. Key, X. Zhu, J. Parks, C. Furdui, P. Stacpoole, J. Martinez, C. E. McCall, M. A. Quinn

This study shows dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction by targeting mitochondrial PDC/PDK energy homeostasis in a mouse model.

eLife · Feb 22, 2021Peer-reviewedImmunology