Author

P. T. Gheinani

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Cell Biology· 1

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. P. Naren· 1 shared A. T. Gewirtz· 1 shared C. Jin· 1 shared C. Li· 1 shared J. Yin· 1 shared S. Sharma· 1 shared T. L. Denning· 1 shared X. Guan· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. P. Naren

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1 paper

Recent·Most cited

Cell BiologybioRxivPreprintNov 16, 2020

Methyltransferase SMYD5 Exaggerates IBD by Downregulating Mitochondrial Functions via Post-translational Control of PGC-1α Stability

Y. Hou, X. Sun, P. T. Gheinani…·C. Li

This study identifies SMYD5 as a driver of IBD by downregulating mitochondrial functions through methylation-dependent degradation of PGC-1α in intestinal epithelial cells.

DOI 10.1101/2020.11.16.385765

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