Author

A. P. Naren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. Beck· 1 shared A. Chandran· 1 shared A. Matson· 1 shared A. Schon· 1 shared A. T. Gewirtz· 1 shared A. Vrzalova· 1 shared B. R. Stripp· 1 shared B. Vyhlidalova· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBiochemistry

A. Beck

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A potential acoustic role for CFTR ion channel in conductive hearing loss

P. Liyanage, K. Mun, G. Carraro, H. L. Ogden, Y. Huang, J. Lee, Y. Ramananda, B. R. Stripp, K. Arora, N. Salomonis, L. L. Hunter, A. P. Naren

This study investigates the role of CFTR in conductive hearing loss by analyzing middle ear cell composition and gene expression in CF and WT mice.

bioRxiv · Sep 23, 2023 · PreprintCell Biology

Methyltransferase SMYD5 Exaggerates IBD by Downregulating Mitochondrial Functions via Post-translational Control of PGC-1α Stability

Y. Hou, X. Sun, P. T. Gheinani, X. Guan, S. Sharma, Y. Zhou, C. Jin, Z. Yang, A. P. Naren, J. Yin, T. L. Denning, A. T. Gewirtz, Z. Xie, C. Li

This study identifies SMYD5 as a driver of IBD by downregulating mitochondrial functions through methylation-dependent degradation of PGC-1α in intestinal epithelial cells.

bioRxiv · Nov 16, 2020 · PreprintCell Biology

Targeting the Pregnane X Receptor Using Microbial Metabolite Mimicry

Z. Dvorak, F. Felix Kopp, C. M. Costello, J. S. Kemp, H. Li, A. Vrzalova, M. Stepankova, I. Iveta Bartonkov, K. Poulikova, B. Vyhlidalova, L. U. Nordstroem, C. Karunaratne, H. Ranhotra, K. S. Mun, A. P. Naren, , R. B. Sartor

This paper develops FKK6, a non-cytotoxic PXR agonist derived from microbial metabolite mimicry, which reduces inflammation and validates the strategy for drug discovery.

bioRxiv · Jan 3, 2020Biochemistry