Protection of Hamsters Challenged with SARS-CoV-2 Variants of Concern by Two Doses of MVC-COV1901 Vaccine Followed by a Single Dose of Beta Variant Version of MVC-COV1901
T.-Y. Kuo, C.-E. Lien, Y.-J. Lin, M.-Y. Lin, C.-C. Wu, W.-H. Tang, J. D. Campbell, P. Traquina, Y.-S. Chuang, L. T. C. Liu, J. Cheng, C. Chen
This study evaluates the efficacy of a vaccine regimen using wildtype and Beta variant S-2P in hamsters against SARS-CoV-2 Delta and VoCs, showing improved neutralization and protection with a mixed-dose schedule.
bioRxiv · Sep 29, 2021 · PreprintImmunology