Author

P. Um

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

W. Bishai· 2 shared A. A. Ordonez· 1 shared A. Apostolos· 1 shared A. Gupta· 1 shared A. K. Singh· 1 shared B. Kana· 1 shared C. K. Bullen· 1 shared J. Huang· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

W. Bishai

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Author profile →

2 papers

Recent·Most cited

A modified BCG with depletion of enzymes associated with peptidoglycan amidation induces enhanced protection against tuberculosis in mice

M. T. Shaku, P. Um, K. Ocius, A. Apostolos, M. Pires, W. Bishai, B. Kana

This paper modifies BCG by depleting MurT-GatD enzymes to unmask NOD-1 ligands, enhancing TB protection in mice.

bioRxiv · May 3, 2023Microbiology

Dynamic single-cell RNA sequencing reveals BCG vaccination curtails SARS-CoV-2 induced disease severity and lung inflammation

A. K. Singh, R. Wang, K. A. Lombardo, M. Praharaj, C. K. Bullen, P. Um, S. Davis, O. Komm, P. B. Illei, A. A. Ordonez, M. Bahr, J. Huang, A. Gupta, K. J. Psoter, S. K. Jain, , W. Bishai

This study uses single-cell RNA sequencing to show BCG vaccination reduces SARS-CoV-2 lung inflammation and disease severity by enhancing antibody production and altering immune cell transcriptional profiles.

bioRxiv · Mar 15, 2022 · PreprintImmunology