Author

P. W. de Waal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

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Research Focus:protein folding & dynamics· 2 Assay:structural biology· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

H. E. Xu· 2 shared K. Melcher· 2 shared X. Wang· 2 shared Y. Jiang· 2 shared B. Dickson· 1 shared E. You· 1 shared E. Zhou· 1 shared H. Zhou· 1 shared

Activity by Year

2019-2020 · peak 1/yr

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10 top collaborators · 36 mutual co-author links

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2 shared papersBiophysics

H. E. Xu

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2 papers

Recent·Most cited

BiophysicsPLOS Computational BiologyPeer-reviewedApr 10, 2020

Molecular mechanisms of fentanyl mediated β-arrestin biased signaling

P. W. de Waal, J. Shi, E. You…·B. Dickson

This paper investigates how fentanyl activates the mu-opioid receptor through beta-arrestin biased signaling using molecular dynamics simulations and validates findings with synthesized compounds.

DOI 10.1371/journal.pcbi.1007394

humanstructural biology

𝕏 PostBluesky

BiophysicsbioRxivOct 29, 2019

A complex structure of arrestin-2 bound to a G protein-coupled receptor

W. Yin, Z. Li, M. Jin…·H. E. Xu

The paper reports the structure of arrestin-2 bound to neurotensin receptor 1, revealing a novel orientation that enables coupling to GPCRs lacking a C-terminal tail.

DOI 10.1038/s41422-019-0256-2

structural biologyexperimental assay

𝕏 PostBluesky