Author

P. Y. Choo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:proteomics· 3 Organism:E. coli· 2 Organism:mouse· 2 Organism:bacteria (other)· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

K. A. Kline· 3 shared J. Chen· 2 shared J. J. Wong· 2 shared K. K. L. Chong· 2 shared A. Firras· 1 shared C. F. Liu· 1 shared C. Liang· 1 shared C. M. B. Ho· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersMicrobiology

K. A. Kline

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4 papers

Recent·Most cited

An essential protease, FtsH, influences daptomycin resistance acquisition in Enterococcus faecalis

Z. J. Nair, I. H. Gao, A. Firras, K. K. L. Chong, P. Y. Choo, K. Pethe, K. A. Kline

This study identifies FtsH as a key factor influencing the speed of daptomycin resistance acquisition in Enterococcus faecalis through its role in regulating HrcA and metabolic processes.

bioRxiv · Jul 31, 2023 · PreprintMicrobiology

Mitoxantrone Targets Both Host and Bacteria to Overcome Vancomycin Resistance in Enterococcus faecalis

R. A. G. da Silva, J. J. Wong, H. Antypas, P. Y. Choo, K. Goh, S. Jolly, C. Liang, L. T. K. Sing, M. Veleba, G. Hu, J. Chen, K. A. Kline

Mitoxantrone synergizes with vancomycin against vancomycin-resistant Enterococcus faecalis by direct antibiotic activity and enhancing host macrophage recruitment and bactericidal activity.

bioRxiv · Oct 24, 2022 · PreprintMicrobiology

Escherichia coli BarA-UvrY regulates the pks island and kills Staphylococci via the genotoxin colibactin

J. J. Wong, K. K. L. Chong, F. K. Ho, C. M. B. Ho, R. Neelakandan, P. Y. Choo, D. Keogh, J. Chen, C. F. Liu, K. A. Kline

This study shows E. coli kills S. aureus via colibactin and identifies BarA-UvrY as a novel regulator of the pks island involved in this process.

bioRxiv · Dec 17, 2021 · PreprintMicrobiology

Spatial and temporal localization of cell wall associated pili in Enterococcus faecalis

P. Y. Choo, C. Wang, M. VanNieuwenhze, K. Kline

This study investigates the spatial and temporal localization of Ebp pili on E. faecalis cell surfaces, finding they are anchored to the cell hemisphere, not at the septum where new cell wall is synthesized.

bioRxiv · Jul 23, 2021Microbiology