Author

Pascal Arp

Erasmus MC

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:DNA methylation· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:cell type annotation· 1 Research Focus:clustering· 1 Research Focus:differential expression· 1 Research Focus:dimensionality reduction· 1

Frequent Co-Authors

André Gerardus UitterlindeniD· 2 shared Joost VerlouwiD· 2 shared Joyce B. J. van MeursiD· 2 shared Athina VidakiiD· 1 shared Carolina Medina‐GómeziD· 1 shared Charles NewcombiD· 1 shared Cindy Germaine BoeriD· 1 shared Dan E. ArkingiD· 1 shared

Activity by Year

2021-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersBioinformatics

André Gerardus UitterlindenORCID

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Author profile →

3 papers

Recent·Most cited

Longitudinal change in mitochondrial heteroplasmy exhibits positive selection for deleterious variants

Lieke M Kuiper, Wen Shi, Joost Verlouw, Yun Soo Hong, Pascal Arp, Daniela Puiu, Linda Broer, Jiaqi Xie, Charles Newcomb, Stephen S. Rich, Kent D. Taylor, Jerome I. Rotter, Joel S. Bader, Eliseo Güallar, Joyce B. J. van Meurs, Dan E. Arking

This study shows that deleterious mitochondrial DNA mutations increase over time and are associated with higher mortality risk, suggesting positive selection rather than genetic drift.

iScience · May 6, 2025Peer-reviewedGenetic & Genomic Medicine

A comprehensive quality control pipeline in human microbiome research for large population studies

Ruolin Li, Joost Verlouw, Cindy Germaine Boer, Pascal Arp, Joyce B. J. van Meurs, André Gerardus Uitterlinden, Robert Kraaij, Carolina Medina‐Gómez

This paper develops a quality control pipeline for human microbiome research in large population studies to improve data reliability and address standardization challenges.

bioRxiv · Jan 20, 2025 · PreprintBioinformatics

Impact of SNP microarray analysis of compromised DNA on kinship classification success in the context of investigative genetic genealogy

Jard H. de Vries, Daniel Kling, Athina Vidaki, Pascal Arp, Vivian Kalamara, Michael M. P. J. Verbiest, Danuta Piniewska-Róg, Thomas J. Parsons, André Gerardus Uitterlinden, Manfred Kayser

This study evaluates how compromised DNA affects kinship classification success using SNP microarray data in investigative genetic genealogy.

Forensic Science International Genetics · Nov 1, 2021Peer-reviewedGenetics