Author

Patricia Castro-Sánchez

Every paper listing this name carries an ORCID.

Identified by ORCID

Patricia Castro-SáncheziD1 paper · Universidad Complutense de Madrid

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

Alexandra Rose TeagleiD· 1 shared Álvaro Gómez‐MoróniD· 1 shared Carlos Carrasco‐PadillaiD· 1 shared David WrightiD· 1 shared Francisco Sánchez‐MadridiD· 1 shared Javier Redondo-MuñóziD· 1 shared Matías Estarás-Hermosel· 1 shared Michael Loran DustiniD· 1 shared

Activity by Year

2023-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

Alexandra Rose TeagleORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintDec 28, 2023

Phosphatases of regenerating liver balance F-actin rearrangements during T cell activation through WD repeat containing protein 1

Óscar Aguilar-Sopeña, Carlos Carrasco‐Padilla, Álvaro Gómez‐Morón…·Pedro Roda‐Navarro

This study shows that PRLs regulate F-actin dynamics during T cell activation by interacting with WDR1, affecting IS formation and cytokine production.

DOI 10.1101/2023.12.28.573244

humanproteomics

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ImmunologybioRxivJun 24, 2023

Deletion of the protein tyrosine phosphatase PTPN22 for adoptive T cell therapy facilitates CTL effector function but promotes T cell exhaustion

Alexandra Rose Teagle, Patricia Castro-Sanchez, Rebecca J Brownlie…·Rose Zamoyska

This study shows that deleting PTPN22 in T cells enhances initial anti-tumor effector function but accelerates T cell exhaustion, with TIM-3 expression linked to IL-2 signaling and NFIL3.

DOI 10.1136/jitc-2023-007614

mouseproteomics

𝕏 PostBluesky