Francisco Sánchez‐Madrid

This study identifies lamin A/C as a regulator of intestinal inflammation and tumorigenesis by modulating immune and stromal cell functions in mouse models and human IBD biopsies.

This study identifies miR-721 as a Th17-derived miRNA that drives autoimmune myocarditis by repressing PPARγ, offering a therapeutic target for treatment.

This study identifies a distinct transcriptional program in mast cells during desensitization, showing it involves active reprogramming rather than passive hyporesponsiveness.

The paper shows that inhibiting IFI16 and AIM2 in myeloid cells from HIV-1 patients reduces Gal-9 and PVR, enhancing CD8+ T-cell responses against HIV-1.

Combining dendritic cell stimulation with anti-TIGIT antibodies enhances memory NK cell cytotoxicity against HIV-1 infected CD4+ T cells in vitro and in vivo.

This study shows that lamin A/C is essential for dendritic cell function in antiviral immunity by modulating epigenetic and transcriptional processes.

The paper shows that in-gel protein digestion with acidic methanol selectively methylates glutamic acid residues, not other methylable residues like aspartic acid.

ReCom improves peptide identification by using a semi-supervised approach with a reference database, increasing performance by 68% over Comet-PTM.