Author

David Wright

University of EdinburghORCID 0000-0001-8666-4155Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

David Wright1 paper

Biology Disciplines

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Molecular Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alasdair J. NisbetiD· 1 shared Amy H. BuckiD· 1 shared Cei Abreu‐GoodgeriD· 1 shared Chanel Milène NaariD· 1 shared Daniel R. G. PriceiD· 1 shared E. Douglas RobertsoniD· 1 shared Graham P. CookiD· 1 shared Hanchen LiiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperMolecular Biology

Alasdair J. NisbetORCID

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3 papers

Recent·Most cited

A non-vesicular Argonaute protein is transmitted from nematode to mouse and is important for parasite survival

Kyriaki Neophytou, Isaac Martínez-Ugalde, Thomas M. Fenton, E. Douglas Robertson, Lewis J. Strachan, V Jayaraman, Yvonne M. Harcus, Chanel Milène Naar, David Wright, Daniel R. G. Price, Ruby F. White, Mike Evans, José Roberto Bermúdez‐Barrientos, Hanchen Li, Rick M. Maizels, , Amy H. Buck

This study identifies an extracellular Argonaute protein from a parasitic nematode that can be internalized by mouse cells and shows it can be targeted for vaccine development.

EMBO Reports · Dec 9, 2025Peer-reviewedMolecular Biology

Phospho-enol pyruvate carboxykinase inhibition limits inflammatory T cell activation

Rebecca J. Brownlie, Helen Carrasco Hope, David Wright, Graham P. Cook, Jose Carlos Perales, Robert J. Salmond

This study shows that PEPCK-M is upregulated in T cells during activation and that its inhibition reduces T cell effector functions and cytokine production.

bioRxiv · Sep 9, 2025 · PreprintImmunology

Essential role of translation factor eIF5a in cytokine production and cell cycle regulation in primary CD8 T lymphocytes

Thomas C. J. Tan, Van C. Kelly, Xiaoyan Zou, David Wright, Tony Ly, Rose Zamoyska

This study shows that eIF5a modification regulates protein translation in CD8 T cells, affecting cytokine production and cell cycle control during activation.

Nature Communications · Dec 17, 2022Peer-reviewedMolecular Biology