Author

Patrizia Locatelli

Institute for Research in Biomedicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:protein structure· 1 Approach:statistical model· 1 Organism:virus· 1

Frequent Co-Authors

Andrea CavalliiD· 2 shared Concetta GuerraiD· 2 shared Giada ZoppiiD· 2 shared Jacopo SgrignaniiD· 2 shared Alberto FurlaniD· 1 shared Alessandra Franzetti-PellandaiD· 1 shared Annalisa Sanga· 1 shared Benedetta CenaiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 40 mutual co-author links

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2 shared papersImmunology

Andrea CavalliORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Dissociation kinetics and avidity gate SARS-CoV-2 neutralization by HR2 stem helix antibodies

Virginia Crivelli, Concetta Guerra, Morgan E. Abernathy, Jacopo Sgrignani, Giada Zoppi, Mia L. Greeson, Annalisa Sanga, Patrizia Locatelli, Jasmine Cantergiani, Benedetta Cena, Tomás Cervantes Rincón, Yu Erica Lee, Michael R. Eso, David Jarrossay, Maira Biggiogero, , Andrea Cavalli

This study identifies hr2.016, a potent and broad SARS-CoV-2 neutralizing antibody, and shows its neutralization depends on kinetic stability and avidity.

bioRxiv · Sep 9, 2026 · PreprintImmunology

AI assisted design of ligands for Lipocalin-2

Jacopo Sgrignani, Sara Buscarini, Patrizia Locatelli, Concetta Guerra, Alberto Furlan, Ying‐Yi Chen, Giada Zoppi, Andrea Cavalli

The paper designs AI-generated miniproteins that bind LCN2 with nanomolar affinity, demonstrating a computational workflow's effectiveness in generating functional binders.

Frontiers in Immunology · Sep 12, 2025Peer-reviewedBiochemistry