Author

Giada Zoppi

Institute for Research in BiomedicineORCID 0000-0002-0737-9100Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:protein structure· 1

Frequent Co-Authors

Andrea CavalliiD· 2 shared Concetta GuerraiD· 2 shared Jacopo SgrignaniiD· 2 shared Patrizia Locatelli· 2 shared Alberto FurlaniD· 1 shared Alessandra Franzetti-PellandaiD· 1 shared Andrew J. deMelloiD· 1 shared Ankit JainiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersImmunology

Andrea CavalliORCID

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3 papers

Recent·Most cited

Dissociation kinetics and avidity gate SARS-CoV-2 neutralization by HR2 stem helix antibodies

Virginia Crivelli, Concetta Guerra, Morgan E. Abernathy, Jacopo Sgrignani, Giada Zoppi, Mia L. Greeson, Annalisa Sanga, Patrizia Locatelli, Jasmine Cantergiani, Benedetta Cena, Tomás Cervantes Rincón, Yu Erica Lee, Michael R. Eso, David Jarrossay, Maira Biggiogero, , Andrea Cavalli

This study identifies hr2.016, a potent and broad SARS-CoV-2 neutralizing antibody, and shows its neutralization depends on kinetic stability and avidity.

bioRxiv · Sep 9, 2026 · PreprintImmunology

Droplet single-cell CRISPR screens identify regulators of T cell-mediated target-cell killing

Giulia Saronio, Gaia Antonini, Ankit Jain, Ian A. Vogel, Rachele Teneggi, Julia Neumann, Giada Zoppi, Yun Ding, Matteo Pecoraro, Mathias Langner, Peter Mirtschink, Stavros Stavrakis, Andrew J. deMello, Roger Geiger

The paper uses droplet single-cell CRISPR screening to identify regulators of T cell-mediated target-cell killing and finds that mTORC1 modulation enhances cytotoxic activity.

bioRxiv · Jun 29, 2026 · PreprintImmunology

AI assisted design of ligands for Lipocalin-2

Jacopo Sgrignani, Sara Buscarini, Patrizia Locatelli, Concetta Guerra, Alberto Furlan, Ying‐Yi Chen, Giada Zoppi, Andrea Cavalli

The paper designs AI-generated miniproteins that bind LCN2 with nanomolar affinity, demonstrating a computational workflow's effectiveness in generating functional binders.

Frontiers in Immunology · Sep 12, 2025Peer-reviewedBiochemistry